Search on: COMPLEMENT C3D 
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Descriptor English:   Complement C3d 
Descriptor Spanish:   Complemento C3d 
Descriptor Portuguese:   Complemento C3d 
Tree Number:   D12.776.124.486.274.250.260.750
Definition English:   A 302-amino-acid fragment in the alpha chain (672-1663) of C3b. It is generated when C3b is inactivated (iC3b) and its alpha chain is cleaved by COMPLEMENT FACTOR I into C3c, and C3dg (955-1303) in the presence COMPLEMENT FACTOR H. Serum proteases further degrade C3dg into C3d (1002-1303) and C3g (955-1001). 
Pharmacological Action:   Immunologic Factors
 
See Related English:   Receptors, Complement 3d
 
History Note English:   2006 (1990) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   24577 
Unique Identifier:   D015933 

Occurrence in VHL:
 

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